In the case of continued pregnancy after the threat of abortion at any time of pregnancy, you should enter 1 dose (1500 IU) of the drug. Then it is necessary to introduce another 1 dose (1500 IU), preferably within 72 hours after delivery, if the child is born Rh-positive. If the presence of more than 15 ml of fetal red blood cells is assumed or a fractional number is obtained as a result of dose calculations, the number of doses should be rounded up to the next integer in the upward direction, for example, when obtaining the result of 1.4, 2 doses (3000 IU) of the drug should be administeredįor prevention in the prenatal period 1 dose of the drug (1500 IU) should be administered approximately at the 28th week of pregnancy. The calculated volume of fetal red blood cells that have entered the mother's bloodstream is divided by 15 ml and the number of doses of D-Vi-Sol (Oral) to be administered is obtained. In cases where a larger volume of fetal red blood cells is expected to enter the mother's bloodstream (more than 30 ml of whole blood or more than 15 ml of red blood cells), the fetal red blood cells should be counted using an approved laboratory technique (for example, the modified Kleihauer and Betke acid wash-staining method) to determine the required dose of the drug.

1 dose (1500 IU) contains a sufficient amount of antibodies to prevent sensitization to the Rh factor, if the volume of fetal red blood cells entering the bloodstream does not exceed 15 ml. The need for a certain dose in the case of passing the full term of pregnancy is different depending on the volume of fetal blood that has entered the mother's bloodstream. In order to avoid the formation of foam, the drug is typed into the syringe with a needle with a wide lumen.įor prevention in the postpartum period 1 dose (1500 IU) of D-Vi-Sol (Oral) should be administered within the first 72 hours after delivery. If it is established that the father is Rh-negative, there is no need to administer the drug.īefore administration, the syringes with the drug are kept for 2 hours at room temperature (20☒ ☌). If the drug is administered before delivery, it is important that the mother receives another 1 dose of the drug after the birth of a Rh-positive child within 72 hours after delivery.

the mother must be Rh-negative and not already sensitized to the Rh0(D) factor.), 1 dose (1500 IU) or 2 doses (3000 IU) once: to the mother - within 72 hours after delivery, in case of termination of pregnancy - immediately after the end of the operation.

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